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cruelty free
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no sulfates
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no silicones
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no parabens
Why Choose Helloskin?
Why Choose Helloskin?
Trusted by Over 40,000 Customers
With a proven track record of delivering exceptional products, our business has earned the trust of over 40,000 satisfied customers.
30 Day Returns & They're Free
We stand behind the quality of our products, which is why we offer a hassle-free 30-day return policy! & They are completely free.
Fast & Free Shipping Over $80 (Shipped from Australia)
All orders placed before 2PM are picked and packed from our Australian warehouse. Orders over $80 are free of charge. $5 Shipping for orders under $80.
Ingredients
Ingredients
PDRN 1% Salmon DNA Multi Peptide Repair Serum
PDRN 1% Salmon DNA Multi Peptide Repair Serum
Multi-Peptide Regeneration Serum · 30ml
or 4 × Dhs. 60.75 with Afterpay · Zip · Klarna
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1% Clinical PDRN
DNA regeneration
8% Matrixyl 3000
Peptide complex
Formulated In-House
No outsourcing
Full Transparency
Ingredients listed
Why Choose Helloskin?
Why Choose Helloskin?
Trusted by Over 40,000 Customers
With a proven track record of delivering exceptional products, our business has earned the trust of over 40,000 satisfied customers.
30 Day Returns & They're Free
We stand behind the quality of our products, which is why we offer a hassle-free 30-day return policy! & They are completely free.
Fast & Free Shipping Over $80 (Shipped from Australia)
All orders placed before 2PM are picked and packed from our Australian warehouse. Orders over $80 are free of charge. $5 Shipping for orders under $80.
Ingredients
Ingredients
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cruelty free
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no sulfates
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no silicones
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no parabens
& THE RESULTS ARE IN
Numbers don't lie.
*Based on survey of 127 verified purchasers. Wrinkle data based on in-vitro multi peptide (Matrixyl 3000) research.
THE SCIENCE OF REGENERATION
What Is PDRN and Why
Is It Taking Over K-Beauty?
PDRN (Polydeoxyribonucleotide) is a DNA fragment extracted from salmon. Originally developed for wound healing, it's the active molecule behind Rejuran Healer — the injectable cult treatment taking Korean clinics by storm. It activates A2A adenosine receptors, triggering collagen synthesis, reducing inflammation, and accelerating cellular repair at the source.
DNA Regeneration
PDRN 1% — Salmon DNA Extract
Activates cellular regeneration through the adenosine salvage pathway. The same molecule used in $1,000+ Rejuran injectable treatments.
Collagen Matrix
Multi Peptide Complex 8% — Matrixyl 3000
Stimulates collagen I, III, IV and fibronectin — the structural scaffolding that keeps skin firm, plump, and resilient. 45% wrinkle reduction in 8-week studies.
Two pathways. Zero overlap. Amplified results.
HOW WE COMPARE
Not All PDRN Is Created Equal
See why 40,000+ Australians choose Helloskin
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BEST VALUE
Helloskin
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K-Beauty Imports | Rejuran Injection | |
|---|---|---|---|
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PDRN Concentration
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1% (declared)
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Unspecified / trace
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Clinical dose
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Added Peptides
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8% Multi Peptide Complex
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None
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None
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Price
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$89 AUD
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$45–65 AUD
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$500–1,200/session
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Formulated In-House
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Own chemists
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OEM / white-label
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N/A
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Concentrations Declared
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Full disclosure
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"Proprietary blend"
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N/A
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Made In Australia
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Yes
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No (imported)
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N/A
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Helloskin vs basic PDRN serums
1% PDRN is only part of the story.
A 1% PDRN / Sodium DNA callout matters, but the formula around it matters too. Helloskin pairs PDRN with peptide support, Niacinamide and a hydrating base so the serum feels like a complete skin routine step, not just a hero ingredient with a nice name.
A hero ingredient can still feel flat if the base is lazy.
PDRN gets the attention, but a serum also needs texture, hydration, support ingredients and consistency. Otherwise it can become another “interesting” bottle that never earns a permanent spot in the routine.
PDRN + peptide support + hydration architecture.
This serum uses 1% PDRN / Sodium DNA with Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Niacinamide and humectants. A PDRN-first formula with a proper support crew, not just a hero ingredient on the label.
Built as a PDRN step with peptide support, Niacinamide and hydration, not just a headline active.
A product can say PDRN on the front and still rely mostly on a surface-level ingredient story.
FULL TRANSPARENCY
Every Ingredient. Every Percentage.
No proprietary blends. No fairy-dusting. No secrets.
Polydeoxyribonucleotide — the same molecule used in Rejuran Healer injectables. Activates A2A adenosine receptors to trigger cellular repair and collagen synthesis.
Palmitoyl Oligopeptide + Palmitoyl Tetrapeptide-7 — a dual-peptide complex shown to stimulate collagen I, III and IV production. 45% wrinkle reduction in studies.
Vitamin B3. Brightens hyperpigmentation, strengthens the skin barrier, regulates sebum and reduces the appearance of enlarged pores.
Supporting Actives
Binds moisture at multiple skin depths — surface plumping and deep dermal hydration simultaneously.
Pro-vitamin that soothes irritation, accelerates barrier repair and locks in moisture post-serum.
Anti-inflammatory. Calms redness, stimulates wound healing and supports PDRN's repair pathway.
Activates skin immunity, reduces inflammation and amplifies PDRN receptor uptake.
Naturally occurring anti-wrinkle compound that energises skin cells and works with Matrixyl.
Inhibits tyrosinase to reduce hyperpigmentation and post-inflammatory redness.
High-potency antioxidant. Neutralises free radical damage and protects active ingredients.
Amino acid that optimises pH for maximum active stability and conditions the moisture barrier.
View Full INCI List ↓
Aqua · Glycerin · Propanediol · Palmitoyl Oligopeptide · Palmitoyl Tetrapeptide-7 · Niacinamide · PDRN (Salmon DNA Extract) · Sodium Hyaluronate · Sodium Hyaluronate Crosspolymer · Panthenol · Adenosine · Centella Asiatica Extract · Beta-Glucan · Glycyrrhiza Glabra Root Extract · Camellia Sinensis Leaf Extract · Hydroxyethylcellulose · Carbomer · Arginine · Phenoxyethanol · Ethylhexylglycerin · Tetrasodium Glutamate Diacetate
REAL RESULTS
What Our Customers Say
“I was spending $800 every 6 months on Rejuran injections. Two months on this and my skin has genuinely never looked better. The texture improvement alone is worth it.”
“Every Korean PDRN serum I've tried hides its concentration. This declares 1% clearly — and delivers results within 2 weeks. Finally, a formula that actually backs itself.”
“As someone with rosacea-prone skin I'm obsessive about ingredients. Zero irritation, visible redness reduction, and the full INCI with every percentage declared. I'm converted.”
“After 3 weeks my husband asked what I'd changed. I've stopped wearing foundation. I didn't expect results this fast.”
YOUR RITUAL
How to Use.
Cleanse
Start with a clean face. Apply after your cleanser while skin is still slightly damp to enhance absorption.
Apply
Dispense 3–4 drops into the palm. Press gently into face and neck — do not rub. Use AM and PM.
Protect
Follow with moisturiser. In the AM, always finish with SPF 30+. Regenerating skin is photosensitive.
EXPECTED RESULTS
Skin calmer, redness visibly reduced. Improved moisture retention. PDRN's anti-inflammatory effect kicks in fast.
Texture noticeably smoother. Plumping begins as the multi peptide complex stimulates collagen production in the dermal layer.
Visible wrinkle reduction. Firmer, more luminous complexion. Maximum results with continued daily use.
💡 Pro Tips
Layer under Retinol at night for amplified anti-ageing results
Ideal post-microneedling or laser — accelerates skin recovery
Safe after chemical peels — supports the healing process
⚠️ Avoid if you have a known salmon or fish allergy
Ingredient notes from our team
PDRN, made less mysterious.
PDRN can sound like clinic jargon very quickly. Here is the bathroom-shelf version: 1% PDRN / Sodium DNA, peptide support, Niacinamide and hydration in a daily serum made for skin that looks fresher, bouncier and more rested.
What is PDRN, really?
PDRN is the short name people use for polydeoxyribonucleotide. On an ingredient list, you will usually see it as Sodium DNA. It sounds very clinic-y, but in this serum we talk about it the way we actually use it: as a cosmetic ingredient for skin that you want to look bouncier, smoother, fresher and more hydrated.
This is not an in-clinic treatment and it is not trying to be one. It is a daily serum built for a normal bathroom shelf, with a texture that layers easily under moisturiser and SPF.
Why the 1% callout matters
A lot of PDRN products make the front of the bottle sound huge, then keep the actual number vague. We prefer being plain about it. This serum uses 1% PDRN / Sodium DNA, so you are not guessing whether the hero ingredient is there as a real formula feature or just a story.
That number matters because PDRN is the reason people are curious about the product in the first place. If we are going to lead with it, we should make it easy to understand.
The peptide support system
PDRN / Sodium DNA is the anchor, but the formula is not trying to ride on one ingredient alone. It also includes Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7, two well-loved cosmetic peptides used in skincare for visible bounce, softness and smoother-looking texture.
That is the point of the system: PDRN gives the product its hero story, while the support peptides, Niacinamide and hydration base make the serum feel more complete in a real routine.
Why Niacinamide sits beside it
Niacinamide is one of those ingredients that earns its place because it plays well with almost everything. In this serum, it helps the formula feel more complete: smoother-looking texture, a more even-looking finish, and skin that feels balanced rather than stripped or tight.
It is not here to steal the spotlight from PDRN. It is here because PDRN makes more sense in a formula that also supports the overall look and feel of the skin barrier.
Hydration is part of the result
A serum can have an exciting hero ingredient and still fail if the skin does not like wearing it. That is why the base matters. Humectants and cushioning ingredients help the finish feel juicy, comfortable and easy to keep using.
Think of the hydration system as the part that makes the PDRN story wearable. The glow you notice first often comes from better hydration and a smoother-feeling surface, while the peptide routine builds with consistency.
How we read the studies
PDRN research is genuinely interesting, but the finished product still needs to be described like skincare, not a medical procedure. Some papers look at PDRN in clinical or lab contexts, and those papers help explain why the ingredient gets attention.
Our job is to translate that without going weird with the claims. So we use the research as ingredient context, keep the product language cosmetic, and focus on what people can actually see and feel: skin that looks plumper, fresher, softer and more radiant.
Who we made it for
This serum is for skin that looks tired, flat, dry, uneven in texture or like it needs a proper reset. It is especially good if you want something more interesting than a basic hydrating serum, but you do not want a routine that feels intense or complicated.
If you already cleanse, moisturise and use SPF, this becomes the ingredient-led serum step in between. Easy, steady, not dramatic.
Where it sits in your routine
Use it after cleansing and before moisturiser. If you use it in the morning, finish with SPF. If you pair it with the PDRN Overnight Mask, use the serum first, let it settle, then apply the mask as your final step on mask nights.
The goal is not to stack every active you own. The goal is a consistent PDRN step that your skin actually wants to keep seeing.
PDRN questions
PDRN serum, explained simply.
The practical questions people ask before adding PDRN to a daily skincare routine.
What is PDRN?
PDRN stands for polydeoxyribonucleotide. In skincare ingredient lists, it often appears as Sodium DNA. We use it as a cosmetic active for skin that you want to look fresher, bouncier, smoother and more hydrated.
What does 1% PDRN mean?
It means PDRN / Sodium DNA is declared at 1% in the formula. We call that out because we do not want the PDRN story to feel vague or decorative.
Is this the same as an in-clinic PDRN treatment?
No. This is a topical cosmetic serum for home use. It is designed to sit in a normal skincare routine after cleansing and before moisturiser.
Which peptides are in the support system?
Alongside 1% PDRN / Sodium DNA, the serum includes Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7. They are included to support visible bounce, softness and smoother-looking texture.
How long until I see results?
Hydration and glow can be noticeable quickly. Visible bounce, smoother-looking texture and a fresher-looking finish usually need consistent use over several weeks.
Can I use it with retinol, vitamin C or niacinamide?
Yes, but keep the routine calm. The serum already includes Niacinamide. If you use retinol, alternate at first. If you use strong vitamin C, many people prefer vitamin C in the morning and PDRN at night.
Can I use it with the PDRN Overnight Mask?
Yes. On mask nights, apply the serum first, let it settle for about a minute, then apply the PDRN Overnight Mask as your final step.
Is it suitable if I have a fish or salmon allergy?
Because PDRN is commonly associated with fish-derived DNA, avoid use or check with a healthcare professional if you have a known fish or salmon allergy.
Is it suitable during pregnancy?
If you are pregnant, breastfeeding, trying to conceive or under medical care, check with your healthcare professional before introducing active skincare.
Where does it sit in my routine?
Apply after cleansing and before moisturiser. Use SPF in the morning. Keep it as your PDRN serum step rather than layering every active in the same routine.
CURATED ROUTINE
The Regeneration Ritual
Three steps. Complete skin renewal. One bundle — and free shipping from the first order.
A gentle pH-balanced cleanser that removes impurities without stripping the skin barrier. Use AM and PM to prepare skin for maximum serum absorption.
Clinical-grade PDRN 1% and Matrixyl 8%. The hero of the ritual.
A nourishing moisturiser with MultiEx BSASM and Shea Butter that locks in hydration, seals in serum actives, and leaves skin soft and supple.
DON'T MISS BATCH 001
Ready to Regenerate?
500 units. One batch. Clinical-grade PDRN + Multi Peptide Complex at concentrations that actually work.
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